YUMI exFAT supports exFAT format & 4GB+ files.Here are the key differences between the variants:

It can be used to automatically create an exFAT boot USB. NOTE: I know you are probably asking, How can you boot from exFAT USB? A YUMI exFAT USB Boot variant is now available and recommended. Distributions can also easily be uninstalled or removed with the tool! Enabling you to Boot Multiple ISO files from the same device. This tool works much like Universal USB Installer, except instead of imaging a single ISO to USB, it can be used to store and run more than one distribution from your thumb drive. YUMI Multiboot Bootable USB Flash Drive Creation You can also use the software to create Bootable Windows Installers, enabling you to easily Install Windows 10 from USB. If you do happen to find a distribution where the installer does not work, please let me know. Though originally intended to be used to boot various “LIVE Linux” Operating Systems and tools, using it to install Linux from a flash drive to a hard drive should work fine with most distributions. This makes for a nicely organized Portable Multiboot Drive that can still be used for traditional storage purposes.

For the most part, files are generally stored within the Multiboot folder. Tools that were amongst the first ever made for the purpose of creating a bootable flash drive. It replaces our old Multiboot ISOS tool and is also the successor to the singular Universal USB Installer (UUI). The YUMI App has been considered by many to be the Best Bootable USB Creator. This Universal tool makes it easy for anyone to create their own customized multi purpose Bootable USB. Use it to boot from USB your favorite Live Linux portable Operating Systems, Linux and Windows Installers, antivirus utilities, disc cloning, backup, penetration testing, diagnostic tools, and much more.

This tool can quickly create a Multiboot bootable USB flash drive containing several different ISO files. YUMI (Your USB Multiboot Installer) is a Multiboot USB Boot Creator that can be used to make a Multisystem flash drive.

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